Region

即将开讲《药物开发中的手性化合物分析方案》

讲座时间:
2020年3月 3二,周四上午 10:00 - 11:30
讲座概要:
作为LC分析核心部分的色谱柱,不同固定相的特点如何?面对五花八门的C18,是否感到困惑?无论当下针对新型冠状病毒正在紧锣密鼓进行中的药物研发,还是日常药物分析方法开发中的色谱柱选择困难症,本次讲座将为您带来答案。
主讲人:
钟旭,北京理工大学硕士学位,拥有7年色谱耗材研发和技术支持经验,并参与小分子样品前处理和LC/MS方法开发等方面的多个研发项目。对HPLC有深入了解,现任艾杰尔-飞诺美市场技术部技术工程师。
推荐听众:
制药行业相关检测人员

马上注册 » 查看更多讲座 »
  1. John Ray,Edna Pang,Dianne Carey.1. Simultaneous determination of indinavir, ritonavir and lopinavir ABT 378 in human plasma by high-performance liquid chromatography[J].Journal of Chromatography,2002,B(May):225-230.
  2. Therese Koal,Heike Burhenne,Regina Ro¨ mling,etc.Quantification of antiretroviral drugs in dried blood spot samples by means of liquid chromatography tandem mass spectrometry[J].Rapid Commun. Mass Spectrom.,2005,19(August):2995-3001.DOI: 10.1002/rcm.2158
  3. Jee Sun Min,Jiseon Kim,Jung Ho Kima,etc.Quantitative determination of carfilzomib in mouse plasma by liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic study[J].Journal of Pharmaceutical and Biomedical Analysis,2017,146(August):341-346.
  4. Ambavaram Vijaya Bhaskar Reddy,Jafariah Jaafar,Azmi Bin Aris,etc.Development and validation of a rapid ultra high performance liquid chromatography with tandem mass spectrometry method for the simultaneous[J].JOURNAL OF SEPARATION SCIENCE,2015,38(15):2580-2587.
  5. Leila P. Somavilla,Matheus W. Lago,Patrícia O. Barth,etc.Assay of tipranavir capsules by a simple stability‑indicating LC–UV method and cytotoxicity study of degraded samples[J].Chemical Papers,2019,73(April):2221-2229.https://doi.org/10.1007/s11696-019-00771-4
  6. Manish Yadav,Ajay Gupta,Puran Singhal,etc.Development and Validation of a Selective and Rapid LCMCM method for the quantification of Abacavir in human plasma[J].Journal of Chromatographic Science,2010,48(September):654-662.
  7. Miss Pasupuleti Laxmi Prasanna,Mrs. Pedapanga Sandhya,Mrs. Pittala Geetha,etc.Novel method development and validation of Bortezomib in bulk and pharmaceutical dosage form by RP-HPLC[J].Journal of Drug Delivery and Therapeutics,2019,9(1):17-21.DOI: http://dx.doi.org/10.22270/jddt.v9i1.2259
  8. applicationLing Zhang, Ying Jiang, Guanghui Jing,etc.A novel UPLC–ESI-MSMS method for the quantitation of disulfiram, its role in stabilized plasma and its application[J].Journal of Chromatography,2013,B(937):54-59.
  9. Christin Durchschein, Antje Hufner, Beate Rinner,etc.Synthesis of novel shikonin derivatives and pharmacological effects of cyclopropylacetylshikonin on melanoma cells[J].molecules,2018,23(X):1-38.https://www.mdpi.com/journal/molecules
  10. A. N. Assimopoulou and V. P. Papageorgiou*.Study on the enantiomeric ratio of the pharmaceutical substances alkannin and shikonin[J].BIOMEDICAL CHROMATOGRAPHY,2004,18(March):791-799.DOI: 10.1002/bmc.390
  11. Jim Küppers, Anna Christina Schulz-Fincke, Jerzy Palus,etc.Convergent synthesis of two fluorescent Ebselen-Coumarin heterodimers[J].pharmaceuticals,2016,9(43):1-11.
  12. Andrew V. Mossine, Allen F. Brooks, Isaac M. Jackson,etc.Synthesis of Diverse C-Labelled PET Radiotracers via direct incorporation of CO2[J].Bioconjug Chem.,2016,18(May):1382-1389.doi:10.1021/acs.bioconjchem.6b00163.
  13. Timothy P. Sheahan, Amy C. Sims, Rachel L. Graham,etc.Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses[J].Sci Transl Med.,2017,28(June):396-415.doi:10.1126/scitranslmed.aal3653.
  14. Travis K. Warren, Robert Jordan, Michael K. Lo,etc.Therapeutic Efficacy of the Small Molecule GS-5734 against Ebola Virus in Rhesus Monkeys[J].Nature,2016,17(March):381-385.oi:10.1038/nature17180.https://doi.org/10.1016/j. vetmic.2018.04.026
  15. B.G. Murphya, M. Perrone, E. Murakami,etc.The nucleoside analog GS-441524 strongly inhibits feline infectious peritonitis (FIP) virus in tissue culture and experimental cat infection studies _ Elsevier Enhanced Reader[J].Veterinary Microbiology,2018,219(April):226-233.
  16. Dustin Siegel,Hon C. Hui,Edward Doerffler,etc.Discovery and Synthesis of a Phosphoramidate prodrug of a pyrrolo Adenine C-Nucleoside GS-5734 for the Treatment of Ebola and Emerging Viruses[J].Journal of Medicinal Chemistry,2017,60(January):1648-1661.DOI: 10.1021/acs.jmedchem.6b01594
  17. Gayle Ritchie, David J. Harvey, Friederike Feldmann,etc.Identification of N-linked carbohydrates from severe acute respiratory syndrome (SARS) spike glycoprotein[J].Virology,2010,10(April):257-269.doi:10.1016/j.virol.2009.12.020.

快速响应通道!HOT!!

完整填写以下信息,技术专家会尽快与您联系!

请详细描述您需要咨询的方法和目前遇到的挑战,并尽量完整地提供细节。