Clarity HPLC信息

优化的寡核苷酸纯化和分析

Clarity 生物解决方案产品组合中的每个产品都是为合成寡核苷酸的高效纯化或表征而专门设计，用于生物研究、治疗方法开发和生化制造。纯化解决方案包括反相 HPLC (RP-HPLC)、离子交换 LC (IEX-LC)、反相小柱 (RPC) 和脱盐，表征解决方案包括高效反相 (RP-LC-MS) 色谱柱。

RPC、HPLC、PREPLC、脱盐和萃取解决方案
DNA、RNA/RNAi、RNAlongmer、硫醇、染色标记/改性寡核苷酸
用于表征/质量控制的高效 LC-MS 方案

3 Phases

Reversed Phase 3

Featured

TECHNICAL NOTE

Analysis of Synthetic Oligonucleotides using Clarity Oligo-SAX - Quaternary Amine Functionalized, Non-porous Particles

Technical note describing characterization of various synthetic OGNs using the new Clarity Oligo-SAX.
TECHNICAL NOTE

Optimizing Sensitivity and Selectivity for the Analysis and Characterization of Synthetic Oligonucleotides via LC/MS

This technical note describes how to achieve the best sensitivity and selectivity for synthetic oligonucleotide analysis via LC/MS.
TECHNICAL NOTE

Optimization of Mobile Phase Composition for the Analysis of Synthetic Oligonucleotides using a Clarity Oligo-XT Column

This technical note describes how to best use new Clarity Oligo-XT columns for high performance analysis of synthetic oligonucleotides.
BROCHURE

Advance Your Oligonucleotide Work

See how Clarity Biosolutions can improve your sample preparation, analysis, and purification of oligonucleotides.

Oligo-RP

颗粒大小(µm)	3, 5, 10
孔径 (Å)	110

Compare All Phases

Oligo-RP 固定相

Analytical LC and Purification Solutions for Oligonucleotide

Clarity Oligo-RP columns have been specifically designed for the reversed phase purification of oligonucleotides with balanced hydrophobicity and polar selectivity. Available in 3, 5, and 10 μm particles, Clarity Oligo-RP allows for high capacity analysis and purification of oligos. Clarity Oligo-RP columns also allow for high loadability and deliver high recovery and purity, from HPLC to Preparative Purification.

A Highly Selective Analysis

Clarity Oligo-RP successfully separates a 40mer from a 39mer DNA oligonucleotide due to its excellent efficiency and resolving power.

Easily Scale from HPLC to Preparative Purification

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<h3>Analytical LC and Purification Solutions for Oligonucleotide</h3>

<p>Clarity Oligo-RP columns have been specifically designed for the reversed phase purification of oligonucleotides with balanced hydrophobicity and polar selectivity. Available in 3, 5, and 10 μm particles, Clarity Oligo-RP allows for high capacity analysis and purification of oligos. Clarity Oligo-RP columns also allow for high loadability and deliver high recovery and purity, from HPLC to Preparative Purification.</p>

<div class="rprow" style="padding-top: 27px">
<h4>A Highly Selective Analysis</h4>
<a href="https://www.phenomenex.com/Application/Detail/16021" target="_blank"><img src="https://www.phenomenex.com/webimage/19clarity_oligo-rp_app16021.png" /></a>

<div>
<p class="app16021">Clarity Oligo-RP successfully separates a 40mer from a 39mer DNA oligonucleotide due to its excellent efficiency and resolving power.</p>
</div>
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<div class="rprow" style="padding-top: 46px">
<h3 style="color: #22bcb9;margin-bottom: 1px">Easily Scale from HPLC to Preparative Purification</h3>
<img src="https://www.phenomenex.com/webimage/19clarity_oligo-rp_dna.png" /></div>
</div>

3 Phases

Reversed Phase 3

技术文档
技术规格
Search FAQ

固定相	颗粒大小(µm)	孔径 (Å)	推荐用途
Oligo-MS	1.7, 2.6	100	Rapid LC/MS analysis and QC of synthetic oligonucleotide research reagents and therapeutics
Oligo-RP	3, 5, 10	110	Purification of synthetic oligonucleotide mixtures
Oligo-XT	1.7, 2.6, 5	100

文档类型:

文件类型	标题
手册	2022/2023 色谱产品指南 (Catalog)	加入我的文档
技术笔记	Analysis of Synthetic Oligonucleotides using Quaternary Amine Functionalized, Non-porous Particles - Clarity Oligo-SAX (TN-1206)	加入我的文档
技术笔记	Automated Method Development of Oligonucleotide in Tissues Using Clarity OTX 96-Well Plate and High Resolution Mass Spectrometry (TN-0097)	加入我的文档
手册	Clarity Biosolutions for Synthetic DNA/RNA	加入我的文档
手册	Improve Your Bioanalytical Assays Today	加入我的文档
Other	Ultimate Guide to Reversed Phase HPLC/UHPLC - Column Selectivity Selection Poster	加入我的文档
手册	寡核苷酸分析更上一层楼	加入我的文档
手册	生物制剂分析解决方案	加入我的文档
手册	生物制药解决方案色谱柱选择参照表	加入我的文档
技术笔记	Avoiding Depurination During Trityl-on Purification (TN-0008)	加入我的文档
手册	Bulk Media Selection Guide	加入我的文档
技术笔记	Oligonucleotide Therapeutics from Biological Matrices (TN-0048)	加入我的文档
技术笔记	Optimization of Mobile Phase Composition for the Analysis of Synthetic Oligonucleotides using a Clarity Oligo-XT Column (TN-1200)	加入我的文档
技术笔记	Synthetic Oligonucleotides by LC/MS (TN-1052)	加入我的文档
Other	USP Allowable Adjustments Guide	加入我的文档
支持文件	Meeting All Your PREP Needs	加入我的文档
Other	Protein and Peptide Users Guide	加入我的文档
支持文件	HPLC Column Care Guide	加入我的文档

固定相: 颗粒大小: 孔径: 长度: 内径:

货号:00B-4441-E0

描述:Clarity® 3 µm Oligo-RP, LC Column 50 x 4.6 mm, Ea

所需柱套:

固定相:C18

填料:Fully Porous Organo-silica

格式:Column

分离模式:Reversed Phase

推荐用途:Purification of synthetic oligonucleotide mixtures

USP名称:L1

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货号	品牌	固定相	颗粒大小 (µm)	孔径 (Å)	长度 (mm)	内径 (mm)	价格

Oligonucleotide

Purification Products

Clarity HPLC信息

优化的寡核苷酸纯化和分析

Featured

Analysis of Synthetic Oligonucleotides using Clarity Oligo-SAX - Quaternary Amine Functionalized, Non-porous Particles

Optimizing Sensitivity and Selectivity for the Analysis and Characterization of Synthetic Oligonucleotides via LC/MS

Optimization of Mobile Phase Composition for the Analysis of Synthetic Oligonucleotides using a Clarity Oligo-XT Column​

Advance Your Oligonucleotide Work

Oligo-RP

Oligo-RP 固定相

Analytical LC and Purification Solutions for Oligonucleotide

A Highly Selective Analysis

Easily Scale from HPLC to Preparative Purification

Optimization of Mobile Phase Composition for the Analysis of Synthetic Oligonucleotides using a Clarity Oligo-XT Column