Comparison of Polymeric and Silica-Based Columns for Oligonucleotide Analysis by Ion-Pair Reversed Phase

Abstract:

When selecting a particle for oligo analysis although a PS-DVB particle might seem like an appropriate choice, one may be making concessions for peak shape and efficiency, which might directly effect method sensitivity. Additionally, separation may not be optimal which can impact impurity analysis and characterization. The bioZen Oligo however, affords scientists a versatile combination of performance gains and robustness, along with improved recovery from bio-inert hardware.

Document Type:

Technical Notes

Industries:

Pharmaceutical/Biopharmaceutical

Techniques:

HPLC / UHPLC

Brands:

bioZen

PDF Link:

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