Extraction of Acidic, Basic, and Neutral Drugs from Human Plasma Comparing Solid Phase Extraction Cartridges

Abstract:

The presence of matrix components in the sample can result in less sensitivity for the target analyte leading to irreproducible data. Other significant chromatographic issues such as high backpressure can result from unwanted impurity build up on the column, which can lead to premature column death. Therefore, determining the appropriate SPE product is a significant step for a successful analytical method.

Document Type:

Technical Notes

Industries:

Clinical

Techniques:

HPLC / UHPLC Sample Prep

Brands:

Kinetex Strata-X

PDF Link:

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