Screening Approach for the Separation of Pharmaceutical Compounds using Lux Polysaccharide-Based Chiral Stationary Phases in SFC Mode (TN-9004)

Abstract:

In this technical note, we present various SFC screening approaches for the chiral separation of a 56-pharmaceutical compound test set using Lux polysaccharide-based chiral stationary phases. The new Lux Amylose-1 provides the largest number of baseline separations. Additional generic chiral separation strategies for SFC are highlighted for increasing success rates.

Document Type:

Technical Notes

Industries:

Pharmaceutical/Biopharmaceutical

Techniques:

HPLC / UHPLC SFC

Brands:

Lux Axia SecurityGuard Standard

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